Cabgolin 0.5 mg is a new long-acting dopamine agonist that is very effective and well-tolerated in patients with pathological hyperprolactinemia (abnormally high levels of prolactin in the bloodstream). It is also used in the prevention of the onset of lactation in the puerperium only for clearly defined medical reasons:
Cabgolin is used to inhibit physiological lactation soon after delivery.
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- After parturition, breastfeeding is contraindicated because of certain medical reasons related to the mother or the baby.
- After stillbirth or abortion
Cabgolin 0.5 mg contains the active ingredient cabergoline, which acts on the pituitary gland at the brain’s base. The stimulation of this gland prevents the production of prolactin hormone. Cabergoline is available under the brand names Dostinex 0.5, and Cabgolin 0.5.
Dose and Method of Administration
Cabergoline uses vary from patient to patient. Consult a doctor for a Cabergoline prescription. Once you get the prescription from a healthcare professional, you can buy Cabergoline online from a reliable source. Cabgolin 0.5 mg is to be administered orally. In research studies, Cabergoline has been mainly administered with meals since the tolerability of this class of medication is improved with food. It is recommended that the medicine be preferably consumed with meals.
Cabgolin should be administered during the first day postpartum to inhibit physiological lactation. The prescribed therapeutic dose is two 0.5 mg tablets as a single dose. Cabergoline tablets are also available as Cabgolin 0.25 mg strength. Find the best place to purchase Cabergoline orders online for discounts and deals.
Treatment of hyperprolactinaemic disorders: The recommended starting dose is 0.5 mg per week, given in one or two per week. The weekly dose should be increased gradually by including 0.5 mg per week at monthly intervals until the appropriate dose-response is attained.
The weekly dose may be administered as a single dose or divided into two or more doses per the patient’s tolerance. The weekly dose may be divided into multiple administrations when doses more than 1 mg a week are to be administered since the tolerability of doses higher than 1 mg administered as a single weekly dose has been evaluated in a very small patient population. Patients should be evaluated to determine the lowest dose that produces the required therapeutic response.
After Cabgolin withdrawal, the condition may recur. However, the suppression of prolactin levels for a longer duration has been observed for several months in some patients. In most females, ovulatory cycles persist for at least six months after discontinuing Cabergoline pills.
In patients with liver insufficiency: Lower doses should be considered in individuals with severe liver impairment who received prolonged treatment with Cabergoline.
The safety and effectiveness of the medicine have not been established in patients under 16 years of age.
Contraindications
Dostinex cabergoline is contraindicated in patients with hypersensitivity to Cabergoline, any other product component, or any ergot alkaloid.
It should not be given in patients with a history of pulmonary, pericardial, and retroperitoneal fibrotic disorders.
Special warnings and precautions for use:
The safety and effectiveness of Cabgolin have not yet been established in patients with kidney and liver disorders. Therefore, it is advisable not to administer the medicine to patients with severe liver disease.
Lower doses should be considered in individuals with severe hepatic impairment who get prolonged treatment with Cabergoline. The medicine should be given with caution to patients with severe cardiovascular disorder, liver disorder, peptic ulcer, renal insufficiency, Raynaud’s syndrome, gastrointestinal bleeding, peptic ulcer, or a history of serious mental disorders. Care should be taken when using Cabgolin concomitantly with other medications to lower blood pressure.
Before initiating long-term therapy:
It is recommended that before initiating treatment with Cabgolin 0.5 mg tablet, all patients undergo a cardiovascular evaluation, including an echocardiogram, to determine the presence of valvular disease.
During long-term therapy, patients suffering from fibrotic disorders should be regularly monitored for possible manifestations of progressive fibrosis. Therefore, during the treatment, attention should be given to the signs and symptoms of:
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- Pleuropulmonary diseases include shortness of breath, dyspnea, persistent cough, or chest pain.
- Kidney impairment may occur with flank and lower limb pain and any possible abdominal masses or tenderness that could indicate retroperitoneal fibrosis.
- Cardiac failure Cases of pericardial fibrosis and valvular have often manifested as cardiac failure. Therefore, valvular fibrosis should be excluded if such symptoms develop.
Undesirable side effects
Women treated with a dose of Cabgolin for inhibition of physiological lactation complained of at least one adverse effect. All side effects are mild to moderate in severity. The most frequently reported adverse effects include vertigo. Dizziness, abdominal pain, and nausea. Rarely, side effects such as drowsiness, vomiting, asthenia, hot flushes, syncope, and epigastric pain.
Cabgolin withdrawal results in the reversal of adverse effects, usually within a few days after discontinuation. The most reported symptoms are headache, nausea, abdominal pain, constipation, vomiting, and hot flashes. Depression, paraesthesia, fatigue, and dyspepsia. Cabergoline generally induces a hypotensive effect in individuals treated chronically; however, symptomatic hypotension or fainting has been rarely reported.
Most side effects are generally dose-related. In patients known to be intolerant of dopaminergic drugs, adverse effects may be lessened by initiating Cabergoline therapy with reduced doses with gradual increase until the therapeutic range is reached. Order the medicine from the comfort of your home at the best price.
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